COL4A3/Tumstatin Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-2160R-PE
Hersteller Artikelnummer:
bs-2160R-PE
Alternativnummer:
BSS-BS-2160R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Mouse
Konjugation:
PE
Alternative Synonym:
Collagen alpha-3IV chain, Alpha 3 type IV collagen, Alpha3 type IV collagen, COL4A 3, COL4A3, Collagen IV alpha 3 polypeptide, Collagen type IV alpha 3 Goodpasture antigen, Collagen type IV alpha 3, Goodpasture antigen, OTTHUMP00000195044, Tumstatin, Col4a3, CO4A3_HUMAN.
COL4A3 (Collagen, type IV, alpha 3) belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. Type IV collagen is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity.
