Activin A receptor, Activin A receptor type II like 1, Activin receptor like kinase 1, Activin receptor-like kinase 1, ACVL1_HUMAN, ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, Osler Rendu Weber syndrome 2, Serine/threonine protein kinase receptor R3, Serine/threonine-protein kinase receptor R3, SKR3, TGF B superfamily receptor type I, TGF-B superfamily receptor type I, TSR-I, TSR1.
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.
