Early B cell factor associated zinc finger protein, Ebfaz, hOAZ, Nur12, OAZ, OLF 1/EBF associated zinc finger, OLF1/EBF associated zinc finger protein, Olf1/EBF-associated zinc finger protein, Roaz, Smad and Olf interacting zinc finger protein, Smad- and Olf-interacting zinc finger protein, Zfp104, ZFP423, zinc finger protein 423, mouse, homolog of, Zinc finger protein 423, ZN423_HUMAN, ZNF423, ZNF423 zinc finger protein 423.
Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
