phospho-C-Myc (Ser62) Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit

Produktübersicht

• Artikelname: phospho-C-Myc (Ser62) Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit
• Artikelnummer: BSS-BS-23392R-BF488
• Hersteller Artikelnummer: bs-23392R-BF488
• Alternativnummer: BSS-BS-23392R-BF488-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: BF488
• Alternative Synonym: Myc(Phospho-Ser62), Myc(Phospho-S62), p-Myc(S62), p-Myc(S62), AU016757, Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, Cellular myelocytomatosis oncogene, MGC105490, MRTL, Myc protein, Myc proto oncogene protein, Myc-related translation/localization regulatory factor, Myc2, myca, Myelocytomatosis oncogene a, Myelocytomatosis oncogene, Niard, Nird, Oncogene Myc, Protooncogene homologous to myelocytomatosis virus, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, v myc avian myelocytomatosis viral oncogene homolog, v myc myelocytomatosis viral oncogene homolog (avian), V-Myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian), zc-myc, MYC_HUMAN.

Produktbeschreibung

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitts lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 4609
• UniProt: P01106
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated Synthesised phosphopeptide derived from human C-Myc around the phosphorylation site of Ser62
• Target-Kategorie: phospho-C-Myc (Ser62)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF()