IL17B Receptor, Interleukin-17 receptor B, IL17RB, IL-17RB, CRL 4, CRL4, Cytokine receptor CRL4, EVI 27, EVI27, IL 17 receptor B, IL 17 receptor homolog 1, IL 17B receptor, IL 17RB, IL 17Rh1, IL17BR, IL17RH1, Interleukin 17 receptor B, Interleukin 17 receptor homolog 1, Interleukin 17 receptor homolog, Interleukin 17B receptor, ecotropic viral integration site 27, interleukin-17 receptor B precursor, MGC5245, I17RB_MOUSE.
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq].
