Vitamin D Receptor Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit
Artikelnummer:
BSS-BS-2987R-BF488
Hersteller Artikelnummer:
bs-2987R-BF488
Alternativnummer:
BSS-BS-2987R-BF488-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human, Rat
Konjugation:
BF488
Alternative Synonym:
NR1I1, PPP1R163, Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.