phospho-14-3-3 protein zeta (Ser58) Polyclonal Antibody, Cy7 Conjugated, Rabbit
Artikelnummer:
BSS-BS-3000R-CY7
Hersteller Artikelnummer:
bs-3000R-Cy7
Alternativnummer:
BSS-BS-3000R-CY7-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, WB
Spezies Reaktivität:
Human
Konjugation:
Cy7
Alternative Synonym:
YWHAEphospho S58, YWHAZphospho S58, 14 3 3, 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta, 14-3-3 protein beta/alpha, KCIP 1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB, YWHAZ, GW128, HS1, KCIP-1, YWHAE, YWHAA, 1433Z_HUMAN, Full=14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1.
Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.