phospho-CRK (Tyr221) Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: phospho-CRK (Tyr221) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-3121R-BIOTIN
• Hersteller Artikelnummer: bs-3121R-Biotin
• Alternativnummer: BSS-BS-3121R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Other
• Konjugation: Biotin
• Alternative Synonym: Adapter molecule crk, Proto-oncogene c-Crk, p38, CRK

Produktbeschreibung

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 1398
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human Crk p38 around the phosphorylation site of Tyr221 [GP(p-Y)AQ]
• Target-Kategorie: phospho-CRK (Tyr221)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)