Phospho-NMDAR2B (Tyr1070) Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit

Produktübersicht

• Artikelname: Phospho-NMDAR2B (Tyr1070) Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit
• Artikelnummer: BSS-BS-3306R-BF350
• Hersteller Artikelnummer: bs-3306R-BF350
• Alternativnummer: BSS-BS-3306R-BF350-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Konjugation: BF350
• Alternative Synonym: MRD6, NR2B, hNR3, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NR3, GRIN2B

Produktbeschreibung

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 2904
• UniProt: Q13224
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1070
• Target-Kategorie: Phospho-NMDAR2B (Tyr1070)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)