phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199) Polyclonal Antibody, APC-Cy5.5 Conjugated, APC/Cy5.5, Rabbit
Artikelnummer:
BSS-BS-3332R-APC-CY5.5
Produktübersicht
Artikelname:
phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199) Polyclonal Antibody, APC-Cy5.5 Conjugated, APC/Cy5.5, Rabbit
Artikelnummer:
BSS-BS-3332R-APC-CY5.5
Hersteller Artikelnummer:
bs-3332R-APC-Cy5.5
Alternativnummer:
BSS-BS-3332R-APC-CY5.5-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, IF, WB
Spezies Reaktivität:
Human, Rat
Konjugation:
APC/Cy5.5
Alternative Synonym:
p85, AGM7, GRB1, IMD36, p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1
Produktbeschreibung
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Produkteigenschaften
Klonalität:
Polyclonal
Konzentration:
1ug/ul
NCBI:
5295
UniProt:
P27986
Puffer:
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle:
KLH conjugated synthetic phosphopeptide derived from human PI3K around the phosphorylation site of p85 alphaTyr467
Target-Kategorie:
phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199)
Anwendungsbeschreibung
Application Verdünnung:
WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
