NF2 Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: NF2 Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BS-34106R
• Hersteller Artikelnummer: bs-34106R
• Alternativnummer: BSS-BS-34106R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: neurofibromatosis type 2, CAN, BANF, bilateral acoustic neuroma, moesin ezrin radixin like protein, Moesin ezrin radizin like protein, merlin, Neurofibromatosis 2, ACN, Bilateral acoustic neuroma, MERL_HUMAN, Merlin, Moesin ezrin radizin like, Moesin-ezrin-radixin-like protein, Neurofibromatosis type 2, Neurofibromin-2, NF 2, Nf2, Neurofibromatosis2, Neurofibromin 2, Neurofibromin2, Schwannomerlin, NF-2, SCH, Schwannomin.

Produktbeschreibung

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 4771
• UniProt: P35240
• Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human NF2
• Target-Kategorie: NF2

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000)