Na+/H+ exchanger 9, NHE 9, NHE9, Putative protein product of Nbla00118, Sodium/hydrogen exchanger 9, Sodium/proton exchanger NHE9, Solute carrier family 9 sodium/hydrogen exchanger isoform 9, Solute carrier family 9 sodium/hydrogen exchanger member 9, Solute carrier family 9 member 9, 5730527A11Rik, 9930105B05, AI854429, FLJ35613, SL9A9_HUMAN.
Slc9a9 (Sodium/hydrogen exchanger 9) or NHE9 may act in electroneutral exchange of protons for Na(+) across membranes. Four isoforms of the Na+/H+ exchanger (NHE6-NHE9) are distributed to intracellular compartments in human cells. They are localized to Golgi and post-Golgi endocytic compartments as follows: mid- to trans-Golgi, NHE8, trans-Golgi network, NHE7, early recycling endosomes, NHE6, and late recycling endosomes, NHE9. The intracellular localization of the NHEs is established by the balance of transport in and out of the post-Golgi compartments as the dynamic membrane trafficking. Their in vivo function is to regulate the pH and monovalent cation concentration in these organelles.
