Recombinant human Cystatin-C protein, N-His, Unconjugated

Artikelnummer: BSS-BS-41175P
Artikelname: Recombinant human Cystatin-C protein, N-His, Unconjugated
Artikelnummer: BSS-BS-41175P
Hersteller Artikelnummer: bs-41175P
Alternativnummer: BSS-BS-41175P-20,BSS-BS-41175P-100,BSS-BS-41175P-500
Hersteller: Bioss
Kategorie: Proteine/Peptide
Applikation: ELISA
Spezies Reaktivität: Other
Konjugation: Unconjugated
Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimers disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
Tag: N-His
NCBI: 1471
UniProt: P01034
Puffer: 0.01M TBS(pH7.4)
Quelle: Recombinant human Cystatin-C protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 27-146/146.
Expression System: E.coli
Reinheit: > 95% as determined by SDS- PAGE