Recombinant mouse ABCB11 protein, Unconjugated

Produktübersicht

• Artikelname: Recombinant mouse ABCB11 protein, Unconjugated
• Artikelnummer: BSS-BS-42133P
• Hersteller Artikelnummer: bs-42133P
• Alternativnummer: BSS-BS-42133P-20,BSS-BS-42133P-100,BSS-BS-42133P-500
• Hersteller: Bioss
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Other
• Konjugation: Unconjugated

Produktbeschreibung

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration.

Produkteigenschaften

• Tag: N-His
• NCBI: 8647
• UniProt: Q9QY30
• Puffer: 0.01M TBS(pH7.4)
• Quelle: Recombinant mouse ABCB11 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 616-750/1321
• Expression System: E.coli
• Reinheit: > 90% as determined by SDS- PAGE