Recombinant human Calreticulin protein, N-His, Unconjugated
Artikelnummer:
BSS-BS-42141P
Hersteller Artikelnummer:
bs-42141P
Alternativnummer:
BSS-BS-42141P-100,BSS-BS-42141P-500
Hersteller:
Bioss
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Other
Konjugation:
Unconjugated
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]