Recombinant human FCGRT&B2M Heterodimer protein, C-His (HEK293), Unconjugated

Produktübersicht

• Artikelname: Recombinant human FCGRT&B2M Heterodimer protein, C-His (HEK293), Unconjugated
• Artikelnummer: BSS-BS-43201P
• Hersteller Artikelnummer: bs-43201P
• Alternativnummer: BSS-BS-43201P-20,BSS-BS-43201P-100,BSS-BS-43201P-500
• Hersteller: Bioss
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Other
• Konjugation: Unconjugated

Produktbeschreibung

FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn a chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and -2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.

Produkteigenschaften

• Tag: C-His
• NCBI: 2217
• UniProt: P55899
• Puffer: 0.01M TBS(pH7.4)
• Quelle: Recombinant human FCGRT&B2M Heterodimer protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 24-297/365&21-119
• Expression System: HEK293
• Reinheit: > 90% as determined by SDS- PAGE