Collagen IV Polyclonal Antibody, APC-Cy7 Conjugated, APC/Cy7, Rabbit

Produktübersicht

• Artikelname: Collagen IV Polyclonal Antibody, APC-Cy7 Conjugated, APC/Cy7, Rabbit
• Artikelnummer: BSS-BS-4595R-APC-CY7
• Hersteller Artikelnummer: bs-4595R-APC-Cy7
• Alternativnummer: BSS-BS-4595R-APC-CY7-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IF, WB
• Spezies Reaktivität: Human
• Konjugation: APC/Cy7
• Alternative Synonym: ICH, HANAC, POREN1, arresten, Collagen alpha-1(IV) chain, COL4A1

Produktbeschreibung

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 1282
• UniProt: P02462
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Collagen alpha-1(IV) chain
• Target-Kategorie: Collagen IV

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)