Caspase-8 subunit p18 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: Caspase-8 subunit p18 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-4683R-BIOTIN
• Hersteller Artikelnummer: bs-4683R-Biotin
• Alternativnummer: BSS-BS-4683R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-Fr, IHC-P
• Spezies Reaktivität: Human, Rat
• Konjugation: Biotin
• Alternative Synonym: ALPS2B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, Apoptosis related cysteine peptidase, Apoptotic cysteine protease, Apoptotic protease Mch 5, Apoptotic protease Mch-5, Apoptotic protease Mch5, CAP 4, CAP4, CASP 8, CASP-8, Caspase-8, Caspase8, CASP8, CASP8_HUMAN, Caspase8, Caspase 8 apoptosis related cysteine peptidase, Caspase8, CED 3, FADD homologous ICE/CED 3 like protease, FADD Homologous ICE/CED3 Like Protease, FADD Like ICE antibody FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, FLJ17672, ICE like apoptotic protease 5, ICE-like apoptotic protease 5, MACH alpha 1/2/3 protein, MACH antibody MACH beta 1/2/3/4 protein antibody MCH 5, MCH5.

Produktbeschreibung

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis, initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 841
• UniProt: Q14790
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Caspase-8 subunit p18
• Target-Kategorie: Caspase-8 subunit p18

Anwendungsbeschreibung

• Application Verdünnung: IHC-P(1:200-400), IHC-F(1:100-500)