phospho-Caspase 6 (Ser257) Polyclonal Antibody, PE Conjugated, Rabbit

Produktübersicht

• Artikelname: phospho-Caspase 6 (Ser257) Polyclonal Antibody, PE Conjugated, Rabbit
• Artikelnummer: BSS-BS-5240R-PE
• Hersteller Artikelnummer: bs-5240R-PE
• Alternativnummer: BSS-BS-5240R-PE-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IF, WB
• Spezies Reaktivität: Mouse
• Konjugation: PE
• Alternative Synonym: Apoptosis-related cysteine protein, Apoptosis Related Cysteine Protease, Apoptotic cysteine protease MCH2, Apoptotic protease MCH 2, Apoptotic protease MCH2, Casp 6, Casp6, Caspase 6 apoptosis related cysteine protease, Caspase 6 precursor, Caspase6, Human cysteine protease Mch2 isoform alpha, Mch 2, Mch2, CASP6_HUMAN.

Produktbeschreibung

Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 839
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257
• Target-Kategorie: phospho-Caspase 6 (Ser257)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)