Phospho-Caspase-9 (Ser196) Polyclonal Antibody, Cy5 Conjugated, Rabbit

Produktübersicht

• Artikelname: Phospho-Caspase-9 (Ser196) Polyclonal Antibody, Cy5 Conjugated, Rabbit
• Artikelnummer: BSS-BS-5241R-CY5
• Hersteller Artikelnummer: bs-5241R-Cy5
• Alternativnummer: BSS-BS-5241R-CY5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Cy5
• Alternative Synonym: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9

Produktbeschreibung

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 842
• UniProt: P55211
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196
• Target-Kategorie: Phospho-Caspase-9 (Ser196)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)