FANCG phospho S383, p-FANCG phospho S383, DNA repair protein XRCC9, DNA-repair protein XRCC9, FAG, Fanconi anaemia complementation group G, Protein FACG, X ray repair, complementing defective, in Chinese hamster cells 9, XRCC9.
FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.
