phospho-MAX protein (Tyr123) Polyclonal Antibody, Unconjugated, Rabbit
Artikelnummer:
BSS-BS-5425R
Hersteller Artikelnummer:
bs-5425R
Alternativnummer:
BSS-BS-5425R-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IF, IHC-Fr, IHC-P, WB
Konjugation:
Unconjugated
Alternative Synonym:
bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, Class D basic helix-loop-helix protein 4, Helix loop helix zipper protein, MAX protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, Myc associated factor X, Myc-associated factor X, MAX_HUMAN, Myc binding novel HLH/LZ protein, Orf 1, Orf1, Protein max.
MAX protein is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
