UNC0646 --- G9a/GLP HMTase Inhibitor, CAS [[1320288-17-2]], Unconjugated

Produktübersicht

• Artikelname: UNC0646 --- G9a/GLP HMTase Inhibitor, CAS [[1320288-17-2]], Unconjugated
• Artikelnummer: BSS-BS-60184C
• Hersteller Artikelnummer: bs-60184C
• Alternativnummer: BSS-BS-60184C-10,BSS-BS-60184C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

UNC0646 is a novel potent, selective and cell permeable inhibitor of the homologous protein lysine methyltransferases, G9a and GLP, with IC50 ~6 nM and 15 nM for G9a and GLP, respectively. It potently inhibits G9a/GLP methyltransferase activity in cells (IC50 ~10 nM in MCF7 cells), and exhibits low toxicity. It is highly selective for G9a/GLP over several other protein lysine and arginine methyltransferases. UNC0646 did not affect G9a co-activator function but selectively decreased G9a co-repressor function for endogenous target genes.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [1320288-17-2]