GSK5959 --- BRPF1 Bromodomain Inhibitor, CAS [[901245-65-6]], Unconjugated

Produktübersicht

• Artikelname: GSK5959 --- BRPF1 Bromodomain Inhibitor, CAS [[901245-65-6]], Unconjugated
• Artikelnummer: BSS-BS-60239C
• Hersteller Artikelnummer: bs-60239C
• Alternativnummer: BSS-BS-60239C-10,BSS-BS-60239C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

GSK5959 is a potent, selective and cell permeable BRPF1 bromodomain inhibitor with IC50 ~ 80 nM. It has >100-fold selectivity for BRPF1 over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains. A cellular protein interaction assay measuring the displacement of NanoLuc-tagged BRPF1 bromodomain from Halotagged histone H3.3 was employed to demonstrate GSK5959s cell permeability and disruption of chromatin binding with IC50 ~0.98 µM.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [901245-65-6]