CB-5083, p97 AAA ATPase Inhibitor, CAS [[1542705-92-9]], Unconjugated

Produktübersicht

• Artikelname: CB-5083, p97 AAA ATPase Inhibitor, CAS [[1542705-92-9]], Unconjugated
• Artikelnummer: BSS-BS-60306C
• Hersteller Artikelnummer: bs-60306C
• Alternativnummer: BSS-BS-60306C-10,BSS-BS-60306C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models . CB-5083 causes rapid and sustained accumulation of poly-ubiquitin in tumor xenografts after a single administration. CB-5083 showed activity to inhibit tumor growth in multiple rodent models of human cancer. Furthermore, CB-5083 appears to exhibit greater potency over current proteasome inhibitors that further validate targeting p97 and protein homeostasis in the treatment of cancer.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [1542705-92-9]