PF-CBP1,CBP/p300 Bromodomain Inhibitor, CAS [[1962928-21-7]], Unconjugated

Produktübersicht

• Artikelname: PF-CBP1,CBP/p300 Bromodomain Inhibitor, CAS [[1962928-21-7]], Unconjugated
• Artikelnummer: BSS-BS-60313C
• Hersteller Artikelnummer: bs-60313C
• Alternativnummer: BSS-BS-60313C-10,BSS-BS-60313C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

PF-CBP1 is a potent and selective CBP/p300 bromodomain inhibitor (IC50 ~125 nM for CBP and 363 nM for p300). It has >100-fold selectivity for CBP over BRD4, and shows selectivity over a panel of other bromodomains. PF-CBP1 reduces LPS-induced IL-1beta, IL-6 and IFN-beta expression in macrophages in vitro. It can also downregulate RGS4 expression in primary cortical neurons in vitro.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [1962928-21-7]