KI-20227, CAS [[623142-96-1]], Unconjugated

Produktübersicht

• Artikelname: KI-20227, CAS [[623142-96-1]], Unconjugated
• Artikelnummer: BSS-BS-6532C
• Hersteller Artikelnummer: bs-6532C
• Alternativnummer: BSS-BS-6532C-10,BSS-BS-6532C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

KI-20227 is a potent and orally active inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R) (IC50 values are 2, 12, 217 and 451 nM for c-Fms, VEGFR-2, PDGFRbeta and c-Kit respectively). KI-20227 suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model. KI-20227 inhibits disease progression in a collagen-induced arthritis mouse model. KI-20227 suppresses experimental autoimmune encephalomyelitis.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [623142-96-1]