UNC569, CAS [[1350547-65-7]], Unconjugated

Produktübersicht

• Artikelname: UNC569, CAS [[1350547-65-7]], Unconjugated
• Artikelnummer: BSS-BS-6575C
• Hersteller Artikelnummer: bs-6575C
• Alternativnummer: BSS-BS-6575C-10,BSS-BS-6575C-2
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. UNC569 is the first small-molecule Mer inhibitor. UNC569 inhibited Mer activation and downstream signaling through ERK1/2 and AKT. Treatment with UNC569 reduced proliferation/survival in liquid culture, decreased colony formation in methylcellulose/soft agar, and increased sensitivity to cytotoxic chemotherapies. Mer receptor tyrosine kinase is ectopically expressed in ALL patient samples and cell lines.

Produkteigenschaften

• Puffer: Powder
• CAS Nummer: [1350547-65-7]