Retinoblastoma binding protein 6, RBBP6, MY038, P2P R, P2PR, p53 associated cellular protein of testis, PACT,proliferationpotentialrelated protein, Protein P2P R, Protein P2PR, Protein RBQ 1, Protein RBQ1, RB binding Q protein 1, RBBP 6, RBQ 1, RBQ1, Retinoblastoma binding protein 6 isoform 3, Retinoblastoma binding Q protein 1, SNAMA, RBBP6_HUMAN.
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. Retinoblastoma binding protein 6 binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
