Ruxolitinib . phosphate salt, CAS [[1092939-17-7]], Unconjugated

Produktübersicht

• Artikelname: Ruxolitinib . phosphate salt, CAS [[1092939-17-7]], Unconjugated
• Artikelnummer: BSS-BS-75541C
• Hersteller Artikelnummer: bs-75541C
• Alternativnummer: BSS-BS-75541C-5,BSS-BS-75541C-25,BSS-BS-75541C-100
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

Water-soluble phosphate salt of Ruxolitinib. Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro. It is investigated against the spread of the SARS-CoV-2 (COVID-19).

Produkteigenschaften

• Puffer: Solid
• CAS Nummer: [1092939-17-7]