Darunavir . ethanolate, CAS [[635728-49-3]], Unconjugated

Produktübersicht

• Artikelname: Darunavir . ethanolate, CAS [[635728-49-3]], Unconjugated
• Artikelnummer: BSS-BS-75605C
• Hersteller Artikelnummer: bs-75605C
• Alternativnummer: BSS-BS-75605C-10,BSS-BS-75605C-50
• Hersteller: Bioss
• Kategorie: Biochemikalien
• Konjugation: Unconjugated

Produktbeschreibung

Darunavir ethanolate is a highly potent HIV protease inhibitor (IC50=3-6nM, depending on laboratory HIV-1 strain), an antiretroviral medication used to treat and prevent HIV/AIDS. The ethanolate formulation has some stability advantages compared to the free base Darunavir (Prod. No. bs-75605C). Darunavir ethanolate is a second generation HIV-1 protease inhibitor that inhibits replication of various laboratory strains and clinical isolates of HIV-1, including those resistant to first generation protease inhibitors. It inhibits cell-free diffusion and cell-to-cell spread of HIV-1 in Jurkat cell populations. Formulations containing darunavir have been used in combination therapy for the treatment of HIV. Shown in a SARS-CoV-2 protease structure model study to potentially bind and inhibit the papain like viral protease (PLVP) of SARS-CoV-2, responsible for COVID-19.

Produkteigenschaften

• Puffer: Solid
• CAS Nummer: [635728-49-3]