phospho-TIRAP (Tyr86) Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: phospho-TIRAP (Tyr86) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-7562R-BIOTIN
• Hersteller Artikelnummer: bs-7562R-Biotin
• Alternativnummer: BSS-BS-7562R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Rat
• Konjugation: Biotin
• Alternative Synonym: Mal, wyatt, BACTS1, MyD88-2, Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, TIRAP

Produktbeschreibung

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 114609
• UniProt: P58753
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic acetylpeptide derived from human TIRAP around phosphorylation site of Tyr86 [KD(p-Y)DV]
• Reinheit: Purified by Protein A.
• Target-Kategorie: phospho-TIRAP (Tyr86)
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)