Marine cembranoid diterpene. Anticancer agent. Inhibits in vivo skin carcinogenesis induced by NOR-1 and TPA. Decreases membrane permeability towards Ca2+, increases degradation of PLA and PLC and decreases levels of COX-2, inhibiting the tumor formation in melanoma models. Cell migration inhibitor in selected cancer cell lines. May be a phosphofructokinase inhibitor. Acetylcholine esterase and ATPase inhibitor. Ichthyotoxin. Tumorigenesis and JB6 cell transformation inhibitor.
Puffer:
Solid
CAS Nummer:
[55038-27-2]
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