SMC6L1, SMC 6, SMC6, SMC6 protein, SMC6 structural maintenance of chromosomes 6 like 1, Structural maintenance of chromosomes 6, Structural maintenance of chromosomes 6 like 1, Structural maintenance of chromosomes protein 6.
SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.