VHL Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: VHL Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-7883R-BIOTIN
• Hersteller Artikelnummer: bs-7883R-Biotin
• Alternativnummer: BSS-BS-7883R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: pVHL, pVHL, G7 protein, Elongin binding protein, HRCA 1, HRCA1, Protein G7, pVHL, RCA 1, RCA1, VHL 1, VHL, VHL_HUMAN, VHL1, VHLH, Von Hippel Lindau disease tumor suppressor, von Hippel Lindau syndrome, von Hippel Lindau tumor suppressor, Von Hippel-Lindau disease tumor suppressor.

Produktbeschreibung

Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 7428
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human VHLH/Von Hippel Lindau
• Target-Kategorie: VHL

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)