CL K1 IIb, Collectin kidney I, MGC129470, MGC129471, CL K1, CL K1 I, CL K1 II, CL K1 IIa, CLK1, COLEC 11, Collectin 11, Collectin kidney protein 1, Collectin sub family member 11, Collectin11, DKFZp686N1868, MGC3279, COL11_HUMAN.
COLEC11 is a 271 amino acid C-type lectin protein that contains a collagen-like domain and a carbohydrate recognition domain, and plays an important role in host-defense. COLEC11 binds to various sugars and LPS (lipopolysaccharides), which include fucose but does not bind to glucose, hnRNP, Beta-1,3-Gal-T3 or mannose. COLEC11 is ubiquitously expressed in most tissues with high expression in kidney, liver, fetal liver, small intestine, thymus, spinal cord, placenta, adrenal gland, pancreas and several cell lines. COLEC11 is a secreted protein and all alternatively spliced isoforms of COLEC11 have oligomeric structures created through disulfide bonding.
