FGFR1OP2 Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: FGFR1OP2 Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BS-8346R
• Hersteller Artikelnummer: bs-8346R
• Alternativnummer: BSS-BS-8346R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC-Fr, IHC-P, WB
• Konjugation: Unconjugated
• Alternative Synonym: DKFZp564O1863, FGFR1 oncogene partner 2, HSPC123, HSPC123 like, FGOP2_HUMAN.

Produktbeschreibung

FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12,8)(p11,p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 26127
• Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human FGFR1OP2
• Target-Kategorie: FGFR1OP2

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)