Galactosyl transferase associated protein, GTAP, NICE 5, NICE5, PRO3094, Protein NICE 5, Protein NICE-5, UB2Q1_HUMAN, UBE2Q, Ube2q1, Ubiquitin carrier protein Q1, Ubiquitin conjugating enzyme E2 Q1, Ubiquitin conjugating enzyme E2Q putative 1, Ubiquitin conjugating enzyme E2Q 1, Ubiquitin conjugating enzyme E2Q family member 1, Ubiquitin protein ligase Q1, Ubiquitin-conjugating enzyme E2 Q1, Ubiquitin-protein ligase Q1.
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (UBE1s), ubiquitin-conjugating enzymes (UBE2s), and ubiquitin-protein ligases (UBE3s). When ubiquitin is activated by a UBE1, it is transferred to the cysteine residue on a UBE2. UBE2 then binds a UBE3, which transfers the ubiquitin from the UBE2 cysteine to a lysine residue on the target protein. Ubiquitin-conjugating enzyme E2 Q1 (UBE2Q1), also known as ubiquitin-protein ligase Q1 or ubiquitin carrier protein Q1, is an 422 amino acid protein belonging to the ubiquitin-conjugating enzyme (UBE2) family. Two named isoforms of UBE2Q1 exist as a result of alternative splicing events.
