1A1, AIM 1, AIM1, MATP, Melanoma antigen AIM1, Membrane associated transporter, Membrane associated transporter protein, Membrane-associated transporter protein, Protein AIM 1, Protein AIM-1, Protein AIM1, S45A2_HUMAN, SHEP5, SLC45A2, Solute carrier family 45 member 2, Underwhite.
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4-bipiridinium), a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.
