HOPX/LAGY Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-9462R-PE
Hersteller Artikelnummer:
bs-9462R-PE
Alternativnummer:
BSS-BS-9462R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, IF
Spezies Reaktivität:
Human, Mouse, Rat
Konjugation:
PE
Alternative Synonym:
HOD, HOP, OB1, LAGY, TOTO, CAMEO, NECC1, SMAP31, Homeodomain-only protein, Lung cancer-associated Y protein, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, HOPX
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
