C19orf45 Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-9681R-PE
Hersteller Artikelnummer:
bs-9681R-PE
Alternativnummer:
BSS-BS-9681R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human, Mouse, Rat
Konjugation:
PE
Alternative Synonym:
chromosome 19 open reading frame 45, C19orf45, CS045_HUMAN, FLJ35784, FLJ56642, hypothetical protein LOC374877, Uncharacterized protein C19orf45.
C19orf45 is a 505 amino acid protein that is encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.