Uncharacterized protein C22orf25, chromosome 22 open reading frame 25, DKFZp 761 P 1121, Hypothetical protein LOC128989, TNG2_HUMAN, TANGO2, Transport and Golgi organization protein 2 homolog.
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf25 gene product has been provisionally designated C22orf25 pending further characterization.
