40 kDa keratin intermediate filament, CK 19, ck19, CK19, CK-19, KRT19, Cytokeratin 19, Cytokeratin-19, k19, k1cs, Keratin 19, Keratin-19, Keratin type I 40 kD, Keratin type i 40kD, Keratin type I cytoskeletal 19, krt19, mgc15366, K1C19_HUMAN, Keratin, type I cytoskeletal 19, Keratin, type I, 40 kd
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
