Cytochrome C Monoclonal Antibody, Biotin Conjugated, Clone: [6B10], Mouse
Artikelnummer:
BSS-BSM-33193M-BIOTIN
Hersteller Artikelnummer:
bsm-33193M-Biotin
Alternativnummer:
BSS-BSM-33193M-BIOTIN-100
Hersteller:
Bioss
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC-Fr, IHC-P, WB
Spezies Reaktivität:
Human, Rabbit, Rat
Konjugation:
Biotin
Alternative Synonym:
Cytochrome c, CYCS
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
