ZO1_HUMAN, Tight junction protein ZO-1, TJP1, ZO1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1, ZO1 tight junction protein,
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.