Stat3 Recombinant Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Stat3 Recombinant Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BSM-52235R
• Hersteller Artikelnummer: bsm-52235R
• Alternativnummer: BSS-BSM-52235R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IF, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: APRF, HIES, ADMIO, Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3

Produktbeschreibung

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 6774
• UniProt: P40763
• Puffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Quelle: Recombinant human Stat3 protein, around N-terminal 1-100aa.
• Target-Kategorie: Stat3

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), FCM(1ug/Test), ICC/IF(1:50-100)