active+pro Caspase 3 (23C9) Monoclonal Antibody, Clone: [23C9], Unconjugated, Rabbit

Produktübersicht

• Artikelname: active+pro Caspase 3 (23C9) Monoclonal Antibody, Clone: [23C9], Unconjugated, Rabbit
• Artikelnummer: BSS-BSM-52439R
• Hersteller Artikelnummer: bsm-52439R
• Alternativnummer: BSS-BSM-52439R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CASP-3, CPP-32, SCA-1, CASP3

Produktbeschreibung

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 1ug/ul
• Klon-Bezeichnung: [23C9]
• NCBI: 836
• UniProt: P42574
• Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: Recombinant protein
• Target-Kategorie: active+pro Caspase 3

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IF(ICC)(1:50-200), IHC()