HP1 alpha Recombinant Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: HP1 alpha Recombinant Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BSM-61202R-BIOTIN
• Hersteller Artikelnummer: bsm-61202R-Biotin
• Alternativnummer: BSS-BSM-61202R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-Fr, IHC-P, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: CBX5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha.

Produktbeschreibung

Component of heterochromatin that recognizes and binds histone H3 tails methylated at Lys-9 (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when Tyr-41 of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 23468
• UniProt: P45973
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human CBX5
• Target-Kategorie: HP1 alpha

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IP(1-2ug)