E3 ubiquitin-protein ligase ZNRF2, ZNRF2, Zinc/RING finger protein 2, RNF202, Protein Ells2.
E3 ubiquitin-protein ligase that plays a role in the establishment and maintenance of neuronal transmission and plasticity. Ubiquitinates the Na+/K+ ATPase alpha-1 subunit/ATP1A1 and thereby influences its endocytosis and/or degradation.