Phospho-CRK (Tyr221) Recombinant Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit

Produktübersicht

• Artikelname: Phospho-CRK (Tyr221) Recombinant Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit
• Artikelnummer: BSS-BSM-61622R-BF594
• Hersteller Artikelnummer: bsm-61622R-BF594
• Alternativnummer: BSS-BSM-61622R-BF594-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: BF594
• Alternative Synonym: Adapter molecule crk, avian sarcoma virus CT10 (v-crk) oncogene homolog, CRK, CRKII, Proto-oncogene c-Crk.

Produktbeschreibung

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Produkteigenschaften

• Klonalität: Recombinant
• Konzentration: Lot dependent
• NCBI: 1398
• UniProt: P46108
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human CRK around the phosphorylation site of Y221
• Target-Kategorie: CRK (Tyr221)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)